Figure 1. Munc18-1 acts as a chaperone for α-synuclein. (A) Healthy cells. (B) EIEE-linked mutants in Munc18-1 cause haploinsufficiency by seeding aggregation of wild-type Munc18-1 and causing aggregation of α-synuclein. (C) α-Synuclein aggregates in the absence of Munc18-1.
Figure 1.

Munc18-1 acts as a chaperone for α-synuclein. (A) Healthy cells. (B) EIEE-linked mutants in Munc18-1 cause haploinsufficiency by seeding aggregation of wild-type Munc18-1 and causing aggregation of α-synuclein. (C) α-Synuclein aggregates in the absence of Munc18-1.

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