Figure 4.
Figure 4. Rho-specific GEF complexes involved in migration and invasion. The Rho-specific GEFs LARG, PDZ-RhoGEF, p115RhoGEF, GEF-H1, and p190RhoGEF regulate migration in different ways depending on the complexes they form. GEFs and GEF-binding proteins are shown in arbitrarily colored boxes. For each complex, the downstream signaling targets are shown as well as the functional outcome. See text for further details.

Rho-specific GEF complexes involved in migration and invasion. The Rho-specific GEFs LARG, PDZ-RhoGEF, p115RhoGEF, GEF-H1, and p190RhoGEF regulate migration in different ways depending on the complexes they form. GEFs and GEF-binding proteins are shown in arbitrarily colored boxes. For each complex, the downstream signaling targets are shown as well as the functional outcome. See text for further details.

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