Proposed sequence of events driving centrosome migration to the cell apical pole. These schemes show a side and top view of cytoskeleton rearrangements after serum withdrawal. Microtubule network densification and actin network contraction break the symmetry of both networks, which results in the production of pushing forces moving the centrosome to the dorsal surface. Upon contact, the centrosome promotes local surface maturation into an apical pole and centriole anchoring and elongation to form the primary cilium.