Rab7 and Rab8 control different nodes in the Notch pathway and are differentially sensitive to Ste14 deficiency. Adult D. melanogaster wings from Ap-Gal4 flies expressing the indicated combinations of UAS-shRNAs at 29°C. Bar, 1 mm. Plotted below the representative wings are the widths of the L4 and L5 vein at the widest part adjacent to the wing margin as a percentage of the total width of the wing for Ap-Gal4 flies expressing the indicated combination of UAS-shRNAs. Data shown are means ± SEM. n = 10. *, P < 0.05 (two-sided t test).