Figure 1.
Motoneuronal regulation of microtubule dynamics. A newly identified Toll-6–FoxO signaling pathway negatively regulates Pav-KLP (Pav) levels at the Drosophila NMJ. Repression of Pav, a negative regulator of microtubule sliding, is required for axonal trafficking of synaptic components and activity-dependent addition of new boutons. Modified from McLaughlin et al. (2016).