FOCAL POINT Brian Mitchell (left), Michael Werner (center), and colleagues (not pictured) determined how the Par complex and the microtubule-stabilizing protein CLAMP allow internal cells to move to the outer layer of the embryo. The image on the right shows the result of depleting CLAMP with a morpholino. Arrows indicate multiciliated cells (blue) that migrated to the embryo’s surface but failed to integrate with the cells already there (red).
PHOTOS COURTESY OF JENNIFER MITCHELL (MITCHELL) AND ELIZABETH ROSS (WERNER)