Figure 2. RhoA knockdown promotes invasive protrusions. (A) 3D invasion (ORIS assay) of siRNA-transfected MDA-MB-231 cells into Matrigel. “No invasion”: stopper removed at the end of assay. Bars, 100 µm. (B) Maximum intensity projection confocal images of F-actin, cortactin, and DAPI-stained cells at the invading front from A. Boxed areas are shown at higher magnification (bottom). Bars: (top) 40 µm; (bottom) 20 µm.
Figure 2.

RhoA knockdown promotes invasive protrusions. (A) 3D invasion (ORIS assay) of siRNA-transfected MDA-MB-231 cells into Matrigel. “No invasion”: stopper removed at the end of assay. Bars, 100 µm. (B) Maximum intensity projection confocal images of F-actin, cortactin, and DAPI-stained cells at the invading front from A. Boxed areas are shown at higher magnification (bottom). Bars: (top) 40 µm; (bottom) 20 µm.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal