Genomic organization of rngo and structure of the Rngo protein. (a) The transcription start of rngo is marked by a black flag, and the stop is marked with a red flag. The position of the P element insertion representing a null allele of rngo is indicated. (b) Predicted structure of the Rngo protein. (c) Alignment of the RVP domain of Rngo with the corresponding region of its yeast (Sc, Saccharomyces cerevisiae), mouse (Mm, Mus musculus), and human (Hs, Homo sapiens) homologues. Residues identical to the consensus sequence are boxed in black. Dm, Drosophila.