FOCAL POINT (Left to right) Boris Rubinstein, Rong Li, Praveen Suraneni, Jay Unruh, and colleagues (not pictured) explored how loss of the Arp2/3 complex affects cell movement. Cells that are able to make ARPC3, an Arp2/3 component, extend ruffle-like lamellipodia (center, arrows) and can crawl in a specific direction. But cells lacking ARPC3 only sprout filopodia-like extensions (right, arrows) and meander.

PHOTO COURTESY OF JAY CASILLAS

or Create an Account

Close Modal
Close Modal