Figure 4. Expression of synaptic UPS reporters in cultured primary neurons from R6/2 and wild-type mice. (A and B) Expression of SNAP25-GFPu/-RFP (A) and PSD95-GFP/-RFP (B) in cultured primary striatal neurons from embryonic wild-type (WT, top panels) and R6/2 (bottom panels) mice. The levels of GFPu in neuronal processes and synapses are higher in R6/2 neurons than in wild-type neurons. Right panels show the ratio (mean + SEM, n = 52) of GFPu/RFP. ***, P < 0.01. Bars, 2.5 μm.
Figure 4.

Expression of synaptic UPS reporters in cultured primary neurons from R6/2 and wild-type mice. (A and B) Expression of SNAP25-GFPu/-RFP (A) and PSD95-GFP/-RFP (B) in cultured primary striatal neurons from embryonic wild-type (WT, top panels) and R6/2 (bottom panels) mice. The levels of GFPu in neuronal processes and synapses are higher in R6/2 neurons than in wild-type neurons. Right panels show the ratio (mean + SEM, n = 52) of GFPu/RFP. ***, P < 0.01. Bars, 2.5 μm.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal