Bidirectional movement of dynein complexes containing IC-2C and IC-1B in neurons. (A) IC-2C dynein. Individual frames of a video (Video 3) showing the movement of dynein puncta in an axon of a cultured hippocampal neuron transfected with mRFP–IC-2C. (B) IC-1B dynein. Individual frames of a video (Video 4) showing movement of dynein puncta in an axon of a cultured hippocampal neuron transfected with mRFP–IC-1B. Arrowheads indicate a puncta moving in the anterograde direction and arrows indicate a puncta moving in the retrograde direction. The time of each frame from the first is indicated on the right. Bars, 10 μm.