A scatter plot of the log₂ fold changes of genes in Oct1^−/− and Lmnb1^Δ/Δ cells. The shaded areas show genes that are either unchanged or moderately dysregulated as defined by a 0.5 cutoff. Only 54 genes are significantly dysregulated in Oct-1–deficient cells and not in Lmnb1^Δ/Δ cells (yellow), whereas 1,030 genes are dysregulated in Lmnb1^Δ/Δ cells and not in Oct-1–deficient cells (orange). Genes outside the shaded areas are those that are significantly dysregulated in both deficient cell types (i.e., the regulation of which is dependent on both Oct-1 and lamin B1). There are also 1,937 genes that are not dysregulated in either cell type (central blue region).