Depletion of Qki in microglia does not affect the expression of Qki in astrocytes and oligodendrocytes and CPZ-induced myelin damage. (A and B) Representative images of IF of Qki-Gfap (A) and Qki-Olig2 (B) in the CCs of Qk-iCKO mice and control (Ctrl) mice 1 wk after tamoxifen injection at P14. (C) Representative images of IF and quantification of oligodendrocyte lineage cells (Olig2-positive) in the CCs of 8-wk-old Qk-iCKO and control mice with tamoxifen injection followed by 4 wk of the CPZ diet or the regular diet. (D) Representative images of IF and quantification of synaptophysin (Syn) in the CCs of 8-wk-old Qk-iCKO and control mice with tamoxifen injection followed by 4- or 6-wk administration of the CPZ diet. n = 4 mice/group. Scale bars: 100 µm. Data are means ± SD. Statistics were calculated using unpaired two-tailed Student’s t test (A and B) and two-way ANOVA with Tukey’s post hoc tests (C and D). **, P < 0.01; ***, P < 0.001. The regions between the dashed lines indicate the CC (C and D). n.s., not significant.