Figure 2.
Principal glycan structures associated with cancer. A listing of the most common glycosylation structures seen during cancer including sLex and sLea, sialyl-Tn antigen, α2,6 sialylation by ST6Gal1, α2,3 sialylation by ST3Gal1, core-fucosylation by FUT8, and the GM3, GD3, and GD2 structures. The name, structure, which glycocalyx backbone it decorates, class of glycan, and which cancers it is associated with are listed for each glycan.