Figure S5.
Nuclear surface area of mutant cells that disrupt chromatin anchoring. Nuclear surface areas of metaphase-arrested cells from the indicated strains were determined as described in Fig. 1 A. Graphs show data from three biological replicates and 50 cells/replicate/cell cycle stage. Error bars are SD. Asterisks indicate a significant difference relative to WT as determined using a two-tailed Student’s t test. **p ≤ 0.01. No significant change (N.S.) between WT and the sir4K1037R mutant cells was observed.

Nuclear surface area of mutant cells that disrupt chromatin anchoring. Nuclear surface areas of metaphase-arrested cells from the indicated strains were determined as described in Fig. 1 A. Graphs show data from three biological replicates and 50 cells/replicate/cell cycle stage. Error bars are SD. Asterisks indicate a significant difference relative to WT as determined using a two-tailed Student’s t test. **p ≤ 0.01. No significant change (N.S.) between WT and the sir4K1037R mutant cells was observed.

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