Outward prejunctional I Na drives the Na + transfer mechanism for lower gap junctional coupling and large total I Na conductance. (A–C) The prejunctional (solid) and postjunctional (dashed) INa are shown as functions of time for the baseline/polarized (green) and mix/homogeneous-polarized (red) distributions for different gap junction conductance ggap of (A) 30, (B) 100, and (C) 300 nS and increasing values of the relative total INa conductance . CV values (in cm/s) are shown for each simulation. Parameters: fNa = 0.7, w = 5 nm. Note the baseline corresponds with gNa of 16 mS/cm2.