Figure S11.

Outward prejunctional I Na drives the Na + transfer mechanism for lower gap junctional coupling and large total I Na conductance. (A–C) The prejunctional (solid) and postjunctional (dashed) INa are shown as functions of time for the baseline/polarized (green) and mix/homogeneous-polarized (red) distributions for different gap junction conductance ggap of (A) 30, (B) 100, and (C) 300 nS and increasing values of the relative total INa conductance fNatotal. CV values (in cm/s) are shown for each simulation. Parameters: fNa = 0.7, w = 5 nm. Note the baseline fNatotal=1 corresponds with gNa of 16 mS/cm2.

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