Figure 9. Postjunctional I Na... | Rockefeller University Press

Figure 9.

$Postjunctional INacontributes proportionally more charge than the conductance fraction. (A–C) The fraction of Na+ charge QNa carried by (A) postjunctional, (B) lateral, and (C) prejunctional INa is shown as a function of fNa, for cleft widths of 10 (left), 20 (middle), and 30 (right) nm and different Na+ channel distributions (baseline/polarized, black; mix/homogeneous-polarized, magenta). The dashed black line corresponds with the conductance fraction on each membrane (fNa/2 on post- and prejunctional; 1 − fNa on the lateral membrane). Parameters: ggap = 100 nS.$

Postjunctional I _Na contributes proportionally more charge than the conductance fraction. (A–C) The fraction of Na⁺ charge Q_Na carried by (A) postjunctional, (B) lateral, and (C) prejunctional I_Na is shown as a function of f_Na, for cleft widths of 10 (left), 20 (middle), and 30 (right) nm and different Na⁺ channel distributions (baseline/polarized, black; mix/homogeneous-polarized, magenta). The dashed black line corresponds with the conductance fraction on each membrane (f_Na/2 on post- and prejunctional; 1 − f_Na on the lateral membrane). Parameters: g_gap = 100 nS.

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