Figure 6.

Working model for the role of robust kinetochore microtubule dynamics in facilitating kinetochore detachment events. Model depicting temporal separation of kinetochore phosphorylation and microtubule dynamics. Left: Under conditions of low tension, the Dam1 kinetochore complex is phosphorylated (center), likely loosening the kinetochore-microtubule attachment strength. Right: Once kinetochores are phosphorylated, robust microtubule dynamics provide mechanical energy to pull the kinetochores away from the dynamic microtubule ends.

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