Figure 2.

Additional echocardiography results. Animals were examined by 2-D and M mode echocardiography. Open bars illustrate Sham-operated and hatched bars illustrate AOB animals. Echocardiography was performed under light anesthesia (0.5% isoflurane via nose cone). Eight animals were examined in each group. (A) Heart rate in beats per minute (BPM) as recorded during the echocardiography session (P = 0.245). (B and C) LV diastolic (B; P = 0.99) and systolic (C; P = 0.90) diameter derived from 2-D echocardiography. (D and E) LV volumes were estimated by assuming a spherical LV to calculate end-diastolic (D; LV EDV; P = 0.99) and end-systolic (E; LV ESV; P = 0.82) volume. Estimated LV volumes were used to calculate the estimated LV ejection fraction: EF% = (EDV − ESV)/EDV (F; P = 0.87). There were no significant differences between the Sham and AOB group for these parameters.

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