Methylation profiles of CpG motifs within gene loci associated to ILCs. (A) ILC1 marker regions (Il2rb, Trerf1, Gpr18, Runx2). (B) ILC2 marker regions (Dhx40, Ptgir, Chdh, Neb, Ptpn13, Rem2, Il5, Bcl11b). (C) ILC3 marker regions (Emb, Lrrk2, Il7r, Blk, Pxdc1, Vipr2). (D) LTi cell marker regions (Ccr6, Ckb, Cdc14a, Stra6, Prelid2, Kit, St3gal3, Itih1). (E) Methylation profiles covering the gene loci of Id2, Tcf7, Zbtb16, Rora, Eomes, and Znf683. Smoothed, linear display of CpG motifs (bar code) methylation values of the DMR (light gray box) and the surrounding gene body (exons in dark gray boxes, TSS indicated by arrow). Colored lines depict the methylation values ranging from 0 (0% methylation) to 1 (100% methylation) for each ILC subset (ILC1 = blue, ILC2 = red, ILC3 = cyan, LTi = dark magenta, NK = black).