Figure S4.
Dynamic patterning of HS modifications within human erythroid and megakaryocyte differentiation. (A) Histograms of HS scFv binding signal in human CD34+ cells from mobilized peripheral blood (donor #2). (B) Flow cytometry plots of HS scFv signal overlaid on the erythroid differentiation markers CD71 and CD235a during day 3, 7, 10, and 14 of erythroid differentiation (donor #1). (C) Flow cytometry plots of HS scFv signal overlaid on the megakaryocyte differentiation markers CD41 and CD42b during day 3, 7, and 14 of megakaryocyte differentiation (donor #1). (D) Distribution of the binding of each HS-specific scFv during day 3, 7, 10, and 14 of erythroid differentiation (donor #1). (E) Distribution of the binding of each HS-specific scFv during day 3, 7, and 14 of megakaryocyte differentiation (donor #1).

Dynamic patterning of HS modifications within human erythroid and megakaryocyte differentiation. (A) Histograms of HS scFv binding signal in human CD34+ cells from mobilized peripheral blood (donor #2). (B) Flow cytometry plots of HS scFv signal overlaid on the erythroid differentiation markers CD71 and CD235a during day 3, 7, 10, and 14 of erythroid differentiation (donor #1). (C) Flow cytometry plots of HS scFv signal overlaid on the megakaryocyte differentiation markers CD41 and CD42b during day 3, 7, and 14 of megakaryocyte differentiation (donor #1). (D) Distribution of the binding of each HS-specific scFv during day 3, 7, 10, and 14 of erythroid differentiation (donor #1). (E) Distribution of the binding of each HS-specific scFv during day 3, 7, and 14 of megakaryocyte differentiation (donor #1).

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal