Figure 4.
Western blot analyses of proteins that coordinate SOCE in soleus muscle. (A and B) Representative immunoblots showing expression levels of the long (STIM1L) and short (STIM1S) STIM1 splice variants (A) and Orai1 (B) in soleus muscle homogenates from WT (n = 4), CASQ1-null (n = 4), and dCASQ-null (n = 4) mice. For Orai1 expression, soleus muscles from constitutive, muscle-specific Orai1 KO (cOrai1 KO) mice were used as a negative control to validate the Orai1 antibody used. MW, molecular weight. (C and D) Relative band intensities (normalized to GAPDH) for each of the proteins shown in A and B. Data are shown as mean ± SEM. *, P = 0.0033, WT vs. CASQ1-null; *, P = 0.000017, WT vs. dCASQ-null; *, P = 0.0031, CASQ1-null vs. dCASQ-null. Source data are available for this figure: SourceData F4.

Western blot analyses of proteins that coordinate SOCE in soleus muscle. (A and B) Representative immunoblots showing expression levels of the long (STIM1L) and short (STIM1S) STIM1 splice variants (A) and Orai1 (B) in soleus muscle homogenates from WT (n = 4), CASQ1-null (n = 4), and dCASQ-null (n = 4) mice. For Orai1 expression, soleus muscles from constitutive, muscle-specific Orai1 KO (cOrai1 KO) mice were used as a negative control to validate the Orai1 antibody used. MW, molecular weight. (C and D) Relative band intensities (normalized to GAPDH) for each of the proteins shown in A and B. Data are shown as mean ± SEM. *, P = 0.0033, WT vs. CASQ1-null; *, P = 0.000017, WT vs. dCASQ-null; *, P = 0.0031, CASQ1-null vs. dCASQ-null. Source data are available for this figure: SourceData F4.

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