Normal development of myeloid cells in Orai3 ^−/− mice. (A and B) Analysis of myeloid cell subsets in the bone marrow (BM) of WT and Orai3^−/− mice. (A) DCs, monocytes, and neutrophils analyzed by flow cytometry. Shown are means ± SEM of five mice per group. (B) Frequencies of pDCs in the BM. Shown are means ± SEM of four mice per group. (C) Frequencies and total numbers of myeloid cells in the peritoneal cavity of WT and Orai3^−/− mice. Shown are means ± SEM of five mice per group. Statistical analysis was performed by unpaired Student’s t test; exact P values are indicated in each panel.