Table 1. Model parameter values applied... | Rockefeller University Press

Table 1.

Model parameter values applied throughout, except in the simulations of 4- and 6-channel couplons, for which the transition rates were changed to 0.125 and 0.125 ms⁻¹

Parameter	Value	Dimension, unit	Description
$k^{+}$	0.001	Time⁻¹, ms⁻¹	Opening transition rate
$k$	2.0	Time⁻¹, ms⁻¹	Closing transition rate
$v$	1.0	None	Allosteric distribution
$v_{V}$	0.8	None	Electrical distribution
$ε_{O O}$	−5.7	Energy, $k T$	Allosteric energy, open
$ε_{C C}$	−0.7	Energy, $k T$	Allosteric energy, close
${I_{1_}}_{h t}$	3.5	time⁻¹, ms⁻¹	Inactivation half time
${I_{2_}}_{h t}$	50	time⁻¹, ms⁻¹	Second inactivation half time
${R_{1_}}_{h t}$	20	time⁻¹, ms⁻¹	Recovery half time
${R_{2_}}_{h t}$	50	time⁻¹, ms⁻¹	Second recovery half time
$R_{C / V}$	5	None	Channel flux ratio C/V
$E_{S}$	−14	Energy, $k T$	Saturation energy

Parameter	Value	Dimension, unit	Description
$k^{+}$	0.001	Time⁻¹, ms⁻¹	Opening transition rate
$k$	2.0	Time⁻¹, ms⁻¹	Closing transition rate
$v$	1.0	None	Allosteric distribution
$v_{V}$	0.8	None	Electrical distribution
$ε_{O O}$	−5.7	Energy, $k T$	Allosteric energy, open
$ε_{C C}$	−0.7	Energy, $k T$	Allosteric energy, close
${I_{1_}}_{h t}$	3.5	time⁻¹, ms⁻¹	Inactivation half time
${I_{2_}}_{h t}$	50	time⁻¹, ms⁻¹	Second inactivation half time
${R_{1_}}_{h t}$	20	time⁻¹, ms⁻¹	Recovery half time
${R_{2_}}_{h t}$	50	time⁻¹, ms⁻¹	Second recovery half time
$R_{C / V}$	5	None	Channel flux ratio C/V
$E_{S}$	−14	Energy, $k T$	Saturation energy