Table 3.

Severe LAD-I–related health issues

​AllisonBrookeCaraCaityColbyaDevEthan
Slow-healing, infected umbilical cord stump ​ ​ • ​ ​ • • 
Rashes • • • • ​ • • 
Skin infections • ​ • • ​ ​ • 
Mouth sores ​ ​ ​ • ​ ​ ​ 
Gingivitis • • • ​ ​ • • 
Ear infections ​ ​ • • ​ • • 
Lung infections (e.g., aspergillus) • • ​ ​ ​ ​ ​ 
Hospitalizations • • • • ​ • • 
a

Infections/health issues were not described for Colby as he was diagnosed immediately after birth (given his siblings’ diagnoses) and received investigational gene therapy within months of birth.

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