Demographic characteristics of study cohort
| | Study participants (n = 76) |
|---|---|
| Sex, n (%) | |
| Male | 41 (54) |
| Race, n (%) | |
| White | 55 (72) |
| Black, African American | 16 (21) |
| Asian | 3 (4) |
| American Indian | 1 (1) |
| Native Hawaiian | 1 (1) |
| Ethnicity, n (%) | |
| Hispanic or Latino | 14 (18) |
| Not Hispanic or Latino | 62 (82) |
| Genetic/syndromic etiology, n (%) | |
| 22q11.2 deletion | 26 (34) |
| CHARGE/CHD7 mutationa | 21 (28) |
| FOXN1 mutation | 2 (3) |
| PAX1 mutation | 1 (1) |
| TBX2 mutation | 1 (1) |
| Diabetic embryopathy | 17 (22) |
| No known mutation/syndrome | 8 (11) |
| Age at time of implantation (months) | |
| Median (Q1; Q3) | 8.9 (4.6; 14.1) |
| Minimum, maximum | 1.1, 53.1 |
| HLA matching | |
| Complete mismatch (6/6) | 35 (46) |
| Partial match (>1) | 35 (46) |
| Ambiguous | 6 (8) |
| Baseline PHA, n (%) | |
| <5,000 cpm | 48 (63) |
| >5,000 cpm | 28 (37) |
| Received immune suppression, n (%) | |
| Yes | 49 (64) |
| No | 27 (36) |
| | Study participants ( |
|---|---|
| | |
| Male | 41 (54) |
| | |
| White | 55 (72) |
| Black, African American | 16 (21) |
| Asian | 3 (4) |
| American Indian | 1 (1) |
| Native Hawaiian | 1 (1) |
| | |
| Hispanic or Latino | 14 (18) |
| Not Hispanic or Latino | 62 (82) |
| | |
| 22q11.2 deletion | 26 (34) |
| CHARGE/ | 21 (28) |
| 2 (3) | |
| 1 (1) | |
| 1 (1) | |
| Diabetic embryopathy | 17 (22) |
| No known mutation/syndrome | 8 (11) |
| | |
| Median (Q1; Q3) | 8.9 (4.6; 14.1) |
| Minimum, maximum | 1.1, 53.1 |
| | |
| Complete mismatch (6/6) | 35 (46) |
| Partial match (>1) | 35 (46) |
| Ambiguous | 6 (8) |
| | |
| <5,000 cpm | 48 (63) |
| >5,000 cpm | 28 (37) |
| | |
| Yes | 49 (64) |
| No | 27 (36) |
CHARGE/CHD7 numbers are based on phenotype or genetic testing.