Stabilization of DNA-PKcs in the presence of 2′3′-cGAMP
| Temperature (C°) . | 46.9 . | 49.5 . | 52.0 . | 54.5 . | 57.1 . | 59.3 . | 60.9 . | 61.7 . |
|---|---|---|---|---|---|---|---|---|
| Mock | 1.0 | 0.8 | 0.8 | 0.7 | 0.5 | 0.4 | 0.4 | 0.4 |
| 2′3′-cGAMP | 1.0 | 1.1 | 1.3 | 1 | 0.6 | 0.5 | 0.5 | 0.5 |
| Temperature (C°) . | 46.9 . | 49.5 . | 52.0 . | 54.5 . | 57.1 . | 59.3 . | 60.9 . | 61.7 . |
|---|---|---|---|---|---|---|---|---|
| Mock | 1.0 | 0.8 | 0.8 | 0.7 | 0.5 | 0.4 | 0.4 | 0.4 |
| 2′3′-cGAMP | 1.0 | 1.1 | 1.3 | 1 | 0.6 | 0.5 | 0.5 | 0.5 |
Ratio of DNA-PKcs over HSP90 protein intensity.