Table 2.

Type I IFN-neutralizing auto-Abs in the study population

Characteristicauto-Ab+, n = 82aNo auto-Ab, n = 236a
Age (years) 69.52 [15.27] 60.88 [15.32] 
≤40 3/29 (10%) 26/29 (90%) 
41–65 20/137 (15%) 117/137 (85%) 
>65 57/148 (39%) 91/148 (61%) 
Unknown 0/4 (0%) 4/4 (100%) 
Sex ​ ​ 
19/107 (18%) 88/107 (82%) 
62/207 (30%) 145/207 (70%) 
Unknown 1/4 (25%) 3/4 (75%) 
WNV groups ​ ​ 
WNVD 81/225 (36%) 144/225 (64%) 
WNVF 1/61 (2%) 60/61 (98%) 
WNVIC 1/32 (3%) 31/32 (97%) 
Subgroups of WNVD ​ ​ 
Non-neuroinvasive WNVD 9/25 (36%) 16/25 (64%) 
Neuroinvasive WNVD ​ ​ 
-All 71/200 (36%) 129/200 (64%) 
-WNE 59/154 (38%) 95/154 (62%) 
-WNM 8/32 (25%) 24/32 (75%) 
-AFP 2/7 (29%) 5/7 (71%) 
-UNS 2/7 (29%) 5/7 (71%) 
Characteristicauto-Ab+, n = 82aNo auto-Ab, n = 236a
Age (years) 69.52 [15.27] 60.88 [15.32] 
≤40 3/29 (10%) 26/29 (90%) 
41–65 20/137 (15%) 117/137 (85%) 
>65 57/148 (39%) 91/148 (61%) 
Unknown 0/4 (0%) 4/4 (100%) 
Sex ​ ​ 
19/107 (18%) 88/107 (82%) 
62/207 (30%) 145/207 (70%) 
Unknown 1/4 (25%) 3/4 (75%) 
WNV groups ​ ​ 
WNVD 81/225 (36%) 144/225 (64%) 
WNVF 1/61 (2%) 60/61 (98%) 
WNVIC 1/32 (3%) 31/32 (97%) 
Subgroups of WNVD ​ ​ 
Non-neuroinvasive WNVD 9/25 (36%) 16/25 (64%) 
Neuroinvasive WNVD ​ ​ 
-All 71/200 (36%) 129/200 (64%) 
-WNE 59/154 (38%) 95/154 (62%) 
-WNM 8/32 (25%) 24/32 (75%) 
-AFP 2/7 (29%) 5/7 (71%) 
-UNS 2/7 (29%) 5/7 (71%) 

aMean [SD], counts, or frequency (%). WNE, WNV encephalitis; WNM, WNV meningitis; AFP, acute flaccid paralysis; UNS, unspecified neurological syndrome.

The round and square brackets indicate that individuals with ages at the extremes of the range are excluded (40 year-old individuals) or included (65-year-old individuals) in this age group.

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