Table 10.

Clinical anxiety and depression categories and comparative HADS scores for the XLA cohort versus UK male norms (median, IQR) (34) and UK male CF patients (mean, SD) (35)

Clinical screening categoriesScoren (%)95% CI
HADS—anxiety (possible) 8–10 6 (18.8%) 8.9–35.3% 
HADS—anxiety (probable) ≥11 5 (15.6%) 6.9–31.8% 
HADS—depression (possible) ≥8–10 2 (6.3%) 1.7–19.9% 
HADS—depression (probable) 11 1 (3.1%) 0.5–15.7% 
Clinical screening categoriesScoren (%)95% CI
HADS—anxiety (possible) 8–10 6 (18.8%) 8.9–35.3% 
HADS—anxiety (probable) ≥11 5 (15.6%) 6.9–31.8% 
HADS—depression (possible) ≥8–10 2 (6.3%) 1.7–19.9% 
HADS—depression (probable) 11 1 (3.1%) 0.5–15.7% 
XLA patients (n = 32)UK male normsP valueUK male CF patientsP value
HADS—Anxiety score 5 (4, 9.5) 5 (2, 8) 0.147 5.7 (3.9) 0.561 
HADS—Depression score 2.5 (0.5, 5.5) 3 (1, 6) 0.873 3.4 (3.3) 0.807 
XLA patients (n = 32)UK male normsP valueUK male CF patientsP value
HADS—Anxiety score 5 (4, 9.5) 5 (2, 8) 0.147 5.7 (3.9) 0.561 
HADS—Depression score 2.5 (0.5, 5.5) 3 (1, 6) 0.873 3.4 (3.3) 0.807 
BronchiectasisNo bronchiectasisP valueBronchiectasis versus UK normsBronchiectasis versus CF patients
HADS—Anxiety score 6 (5, 10) 4 (1, 7) 0.079 0.024 0.101 
HADS—Depression score 4.5 (2, 7) 0 (0, 2) 0.003 0.066 0.122 
BronchiectasisNo bronchiectasisP valueBronchiectasis versus UK normsBronchiectasis versus CF patients
HADS—Anxiety score 6 (5, 10) 4 (1, 7) 0.079 0.024 0.101 
HADS—Depression score 4.5 (2, 7) 0 (0, 2) 0.003 0.066 0.122 

Values in italics are those that are statistically significant (P <0.05).

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