Table 2.

IVM to study the dynamics of individual cells

Event Organ Probe Reference 
Neuronal morphology of hippocampal neurons Brain Thy1-GFP mice, dextran Barretto et al., 2011  
Neuronal circuitry Brain Brainbow mice Livet et al., 2007  
Dendritic spine development in the cortex Brain YFP H-line mice Pan and Gan, 2008  
Calcium imaging in the brain Brain GCAMP Zariwala et al., 2012  
Natural killer cell and cytotoxic T cell interactions with tumors Xenograft mCFP , mYFP Deguine et al., 2010  
Neutrophil recruitment in beating heart Heart Dextran, CX3CR1-GFP mice Li et al., 2012  
Immune cells in the central nervous system Brain Dextran, CX3CR1-GFP, LysM-GFP and CD11c-YFP mice Nayak et al., 2012  
Dendritic cells migration Skin YFP, VE-caherin RFP mice, dextran Nitschké et al., 2012  
CD8+ T cells interaction with dendritic cells during viral infection Lymph nodes EGFP, Dextran, SHG Hickman et al., 2008  
B cells and dendritic cells interactions outside lymph nodes Lymph nodes EGFP Qi et al., 2006  
Change in gene expression during metastasis Xenograft  Pinner et al., 2009  
Invasion and metastasis in head and neck cancer Xenograft YFP, RFP-lifeact, dextran Amornphimoltham et al., 2013  
Fibrosarcoma cell migration along collagen fibers Dorsal skin chamber SHG, EGFP, DsRed, Dextran Alexander et al., 2008  
Long term imaging mammary tumors and photo-switchable probes Mammary window Dendra-2 Kedrin et al., 2008; Gligorijevic et al., 2009  
Long term imaging liver metastasis through abdominal window Liver SHG, Dendra2, EGFP Ritsma et al., 2012b  
Macrophages during intravasation in mammary tumors Xenograft EGFP, SHG, dextrans Wang et al., 2007; Wyckoff et al., 2007  
Melanoma collective migration Dorsal skin Chamber SHG, THG, EGFP, Dextran Weigelin et al., 2012  
Hematopoietic stem cells and blood vessel Skullcup Dextran Lo Celso et al., 2009  
Epithelial stem cells during hair regeneration Skin H2B-GFP mice Rompolas et al., 2012  
Event Organ Probe Reference 
Neuronal morphology of hippocampal neurons Brain Thy1-GFP mice, dextran Barretto et al., 2011  
Neuronal circuitry Brain Brainbow mice Livet et al., 2007  
Dendritic spine development in the cortex Brain YFP H-line mice Pan and Gan, 2008  
Calcium imaging in the brain Brain GCAMP Zariwala et al., 2012  
Natural killer cell and cytotoxic T cell interactions with tumors Xenograft mCFP , mYFP Deguine et al., 2010  
Neutrophil recruitment in beating heart Heart Dextran, CX3CR1-GFP mice Li et al., 2012  
Immune cells in the central nervous system Brain Dextran, CX3CR1-GFP, LysM-GFP and CD11c-YFP mice Nayak et al., 2012  
Dendritic cells migration Skin YFP, VE-caherin RFP mice, dextran Nitschké et al., 2012  
CD8+ T cells interaction with dendritic cells during viral infection Lymph nodes EGFP, Dextran, SHG Hickman et al., 2008  
B cells and dendritic cells interactions outside lymph nodes Lymph nodes EGFP Qi et al., 2006  
Change in gene expression during metastasis Xenograft  Pinner et al., 2009  
Invasion and metastasis in head and neck cancer Xenograft YFP, RFP-lifeact, dextran Amornphimoltham et al., 2013  
Fibrosarcoma cell migration along collagen fibers Dorsal skin chamber SHG, EGFP, DsRed, Dextran Alexander et al., 2008  
Long term imaging mammary tumors and photo-switchable probes Mammary window Dendra-2 Kedrin et al., 2008; Gligorijevic et al., 2009  
Long term imaging liver metastasis through abdominal window Liver SHG, Dendra2, EGFP Ritsma et al., 2012b  
Macrophages during intravasation in mammary tumors Xenograft EGFP, SHG, dextrans Wang et al., 2007; Wyckoff et al., 2007  
Melanoma collective migration Dorsal skin Chamber SHG, THG, EGFP, Dextran Weigelin et al., 2012  
Hematopoietic stem cells and blood vessel Skullcup Dextran Lo Celso et al., 2009  
Epithelial stem cells during hair regeneration Skin H2B-GFP mice Rompolas et al., 2012  

or Create an Account

Close Modal
Close Modal