Summary of kinases used in this study
| Kinases | Required for activation of | Main mitotic functions | Effects of deficiency |
| Cdk1 | AurA, Plk1, and AurB | G2/M transition | G2 arrest |
| Plk1 | N/A | Spindle formation | Prophase/prometaphase arrest |
| AurA | Plk1 in G2 | Spindle MT stability and chromosome alignment | Mitotic delay and aneuploidy |
| AurB | N/A | Chromosome alignment, SAC, and cytokinesis | Cytokinesis failure and binucleate cells |
| AurA/AurB | N/A | Spindle MT stability, chromosome segregation, and anaphase spindle disassembly | No chromosome disjunction and polyploidy |
| Kinases | Required for activation of | Main mitotic functions | Effects of deficiency |
| Cdk1 | AurA, Plk1, and AurB | G2/M transition | G2 arrest |
| Plk1 | N/A | Spindle formation | Prophase/prometaphase arrest |
| AurA | Plk1 in G2 | Spindle MT stability and chromosome alignment | Mitotic delay and aneuploidy |
| AurB | N/A | Chromosome alignment, SAC, and cytokinesis | Cytokinesis failure and binucleate cells |
| AurA/AurB | N/A | Spindle MT stability, chromosome segregation, and anaphase spindle disassembly | No chromosome disjunction and polyploidy |
N/A, not available.