Phenotypes induced by the expression of N-terminal AKAP450 fragments
| AKAP450 fragments | Golgi integrity | Golgi positioning | Secretion | CTR/GA reorientation | Directional migration | Primary cilium formation |
| AKAP4501–3,899 aa | +++ | +++ | +++ | +++ | +++ | +++ |
| AK1 domain1–1,029 aa | ++ | − | ++ | +/− | − | − |
| AK1B domain159–463 aa | − | +++ | ++ | ++ | + | − |
| AKAP450 fragments | Golgi integrity | Golgi positioning | Secretion | CTR/GA reorientation | Directional migration | Primary cilium formation |
| AKAP4501–3,899 aa | +++ | +++ | +++ | +++ | +++ | +++ |
| AK1 domain1–1,029 aa | ++ | − | ++ | +/− | − | − |
| AK1B domain159–463 aa | − | +++ | ++ | ++ | + | − |
+++, normal phenotype; ++, slightly affected; +, mildly affected; +/−, moderately affected; −, strongly affected.
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