Table I. Microarray analysis of... | Rockefeller University Press

Table I.

Microarray analysis of Mesp1-GFP–expressing cells

Category	Up-regulated genes
Transcription factors and chromatin remodeling	Hoxb1 (3.7), Foxc1* (3.5), *Lmo1* (3.2), Foxc2* (3.0), Foxf1a (2.9), *Pdlim4* (2.9), Isl1 (2.8), Hoxb2 (2.6), *Mesp1* (2.6), *Etv2* (2.4), Prrx2 (2.4), *Tbx3* (2.4), Tbx6 (2.4), *Snai1* (2.4), *Lef1* (2.3), Msx2 (2.3), *Smarcd3* (2.3), Mesp2 (2.2), Tbx2 (2.2), Evx1 (2.1), Hand1 (2.1), *Meis2* (2.1), *Prdm6* (2.1), *Zcchc12* (2.1), *Gata4* (2), *Hand2* (2), *Klhl6* (2), Msx1 (2), Six2 (2), Twist1* (2), Vax1 (2), Zeb2* (2), Bhlhe22 (1.9), *Tbx20* (1.9), Zbtb7c (1.9), *Ets1* (1.9), Hey2* (1.9), Smad6* (1.9), Zdhhc20* (1.9), Zcchc24* (1.9), *Hmga2* (1.8), Hoxd1 (1.8), *Pdlim5* (1.8), *Tshz1* (1.8), Zfp516 (1.8), Hey1* (1.7), *Smad1* (1.7), Cbx4 (1.7), Zfp423 (1.7), *Foxh1* (1.6), Nfatc1* (1.6), Twist2* (1.6), Zeb1* (1.6)
Signaling pathways (other than receptors)
Notch	*Dll1* (2.1), *Dll3* (2.0), *Hey2* (1.9), Hey1 (1.7)
Wnt	*Wnt5a* (3), Wnt2 (2.8), Wnt5b (2.1), Apcdd1 (1.8), *Lef1* (1.8), Wnt3 (1.7)
FGF	*Fgf3* (2.3), Fgf15 (1.7), Fgf10 (1.6)
TGF-b	Gdf10 (2.7), Tgfb2 (2.0), *Lefty2* (1.9), Tgfbi (1.9), *Tgfb1i1* (1.8), *Vasn* (1.7)
Bmp	*Bmper* (2.4), Bmp4 (2.0), Bambi (1.7), Bmp6 (1.6), Smad6 (1.9), *Smad1* (1.6)
Others	*Rasgrp3* (2.4), *Rgs5* (2.7), *Crabp1* (2.7), Htr1d (2.6), Adcyap1r1 (2.5), S1pr5 (2.4), *Ptgds* (2.3), *Dusp9* (2.3), *Cap2* (2.0), *Dlc1* (1.9), Tnfsf13b (1.9), *Adcy3* (1.9), Dok4 (1.9), *Efna3* (1.8), *Braf* (1.7), Prkd1 (1.7), *Alox15* (1.6), Pgr (1.6), *Vegfc* (1.6)
Membrane proteins and receptors	*Pcdh19* (3.1), *Pdgfra* (3.1), *Ceacam10* (2.9), Cmklr1 (2.5), *Gp1bb* (2.5), Plac1 (2.5), Cacna1c (2.4), *Odz4* (2.3), *Nrp2* (2.3), *Vldlr* (2.3), Cdh4 (2.3), *Pcdh18* (2.3), Adrb1 (2.2), Kdr (2.1), Rftn1 (2.1), Unc5c (2.1), Lhfp (2.0), Kcnd3 (2.0), *Il13ra1* (2.0), Amhr2 (2.0), Cd160 (1.9), *L1cam* (1.9), *Cxcr4* (1.9), Aplnr (1.9), Pcdh7 (1.9), Cxcr7 (1.9), *Slc4a4* (1.9), Gpr177 (1.8), Itga8 (1.8), *Prtg* (1.8), Ednra (1.8), Kcnc1 (1.8), *Cdh11* (1.7), Pcdh7 (1.7), *Pdgfrb* (1.7), *Gfra2* (1.7), Trpc3 (1.7), *Nrp1* (1.7), *Cdh2* (1.7), Tmem88 (1.6), Il1rap (1.6), *Lrp1* (1.6), Ms4a4d (1.6), *Kctd15* (1.5)
Extracellular matrix	Col6a1 (3.5), Col9a1 (2.6), Emid2 (2.4), Leprel1 (2.3), *Fbln2* (2.2), Fbln7 (2.1), Lor (2.0), *Col13a1* (2.0), *Fn1* (1.9), *Has2* (1.8), *Vcan* (1.6), Flnb (1.6), Mmp2 (1.6)
Others	Spp1 (5.8), *Fabp4* (5.5), H60a (4.5), Ugt1a1 (4.0), Papss2 (3.8), Agpat9 (3.1), Ccdc109b (2.8), *Phlda2* (2.6), Egln3 (2.5), Gna14 (2.5), *Pcsk5* (2.4), Atp1a2 (2.4), Dock10 (2.3), *Hs3st3b1* (2.3), Morc4 (2.3), *Chst2* (2.3), *Pmp22* (2.3), *Adamts20* (2.2), *St6galnac4* (2.2), Exoc3l (2.2), Fam123c (2.1), *Myl7* (2.1), Prdm6 (2.1), Susd5 (2.1), *Rbm24* (2.1), Siah2 (2.1), *Mex3b* (2.1), Chst7 (2.0), Nin (2.0), *Actc1* (2.0), Kif26b (2.0), Ccnd2 (2.0), Itih5 (1.9), *Man1c1* (1.9), Cbln1 (1.9), *Mn1* (1.9), *Sh3bp1* (1.9), Fam82a1 (1.8), *Olfm1* (1.8), Serpinb9 (1.8), *Cdkn1c* (1.8), *Phldb2* (1.8), Pmaip1 (1.8), *Gas1* (1.8), Abtb2 (1.8), *Adamts3* (1.7), *Sgcb* (1.7), *Sbsn* (1.7), Cyp2s1 (1.7), Adam19 (1.7), Brp44 (1.7), Cyp4f15 (1.7), Dclk1 (1.7), Slco3a1 (1.7), Bace2 (1.7), Car3 (1.7), Aard (1.6), Oaf (1.6), Zadh2 (1.6), As3mt (1.6), Grrp1 (1.6), Ablim1 (1.6), Fam122b (1.6), Gne (1.6), Ptprm (1.6), Rps6ka6 (1.6), Lmna (1.5), Man1a (1.5), Pwwp2b (1.5)

Category	Up-regulated genes
Transcription factors and chromatin remodeling	Hoxb1 (3.7), Foxc1* (3.5), Lmo1 (3.2), Foxc2* (3.0), Foxf1a (2.9), Pdlim4 (2.9), Isl1 (2.8), Hoxb2 (2.6), Mesp1 (2.6), Etv2 (2.4), Prrx2 (2.4), Tbx3 (2.4), Tbx6 (2.4), Snai1 (2.4), Lef1 (2.3), Msx2 (2.3), Smarcd3 (2.3), Mesp2 (2.2), Tbx2 (2.2), Evx1 (2.1), Hand1 (2.1), Meis2 (2.1), Prdm6 (2.1), Zcchc12 (2.1), Gata4 (2), Hand2 (2), Klhl6 (2), Msx1 (2), Six2 (2), Twist1* (2), Vax1 (2), Zeb2* (2), Bhlhe22 (1.9), Tbx20 (1.9), Zbtb7c (1.9), Ets1 (1.9), Hey2* (1.9), Smad6* (1.9), Zdhhc20* (1.9), Zcchc24* (1.9), Hmga2 (1.8), Hoxd1 (1.8), Pdlim5 (1.8), Tshz1 (1.8), Zfp516 (1.8), Hey1* (1.7), Smad1 (1.7), Cbx4 (1.7), Zfp423 (1.7), Foxh1 (1.6), Nfatc1* (1.6), Twist2* (1.6), Zeb1* (1.6)
Signaling pathways (other than receptors)
Notch	Dll1 (2.1), Dll3 (2.0), Hey2 (1.9), Hey1 (1.7)
Wnt	Wnt5a (3), Wnt2 (2.8), Wnt5b (2.1), Apcdd1 (1.8), Lef1 (1.8), Wnt3 (1.7)
FGF	Fgf3 (2.3), Fgf15 (1.7), Fgf10 (1.6)
TGF-b	Gdf10 (2.7), Tgfb2 (2.0), Lefty2 (1.9), Tgfbi (1.9), Tgfb1i1 (1.8), Vasn (1.7)
Bmp	Bmper (2.4), Bmp4 (2.0), Bambi (1.7), Bmp6 (1.6), Smad6 (1.9), Smad1 (1.6)
Others	Rasgrp3 (2.4), Rgs5 (2.7), Crabp1 (2.7), Htr1d (2.6), Adcyap1r1 (2.5), S1pr5 (2.4), Ptgds (2.3), Dusp9 (2.3), Cap2 (2.0), Dlc1 (1.9), Tnfsf13b (1.9), Adcy3 (1.9), Dok4 (1.9), Efna3 (1.8), Braf (1.7), Prkd1 (1.7), Alox15 (1.6), Pgr (1.6), Vegfc (1.6)
Membrane proteins and receptors	Pcdh19 (3.1), Pdgfra (3.1), Ceacam10 (2.9), Cmklr1 (2.5), Gp1bb (2.5), Plac1 (2.5), Cacna1c (2.4), Odz4 (2.3), Nrp2 (2.3), Vldlr (2.3), Cdh4 (2.3), Pcdh18 (2.3), Adrb1 (2.2), Kdr (2.1), Rftn1 (2.1), Unc5c (2.1), Lhfp (2.0), Kcnd3 (2.0), Il13ra1 (2.0), Amhr2 (2.0), Cd160 (1.9), L1cam (1.9), Cxcr4 (1.9), Aplnr (1.9), Pcdh7 (1.9), Cxcr7 (1.9), Slc4a4 (1.9), Gpr177 (1.8), Itga8 (1.8), Prtg (1.8), Ednra (1.8), Kcnc1 (1.8), Cdh11 (1.7), Pcdh7 (1.7), Pdgfrb (1.7), Gfra2 (1.7), Trpc3 (1.7), Nrp1 (1.7), Cdh2 (1.7), Tmem88 (1.6), Il1rap (1.6), Lrp1 (1.6), Ms4a4d (1.6), Kctd15 (1.5)
Extracellular matrix	Col6a1 (3.5), Col9a1 (2.6), Emid2 (2.4), Leprel1 (2.3), Fbln2 (2.2), Fbln7 (2.1), Lor (2.0), Col13a1 (2.0), Fn1 (1.9), Has2 (1.8), Vcan (1.6), Flnb (1.6), Mmp2 (1.6)
Others	Spp1 (5.8), Fabp4 (5.5), H60a (4.5), Ugt1a1 (4.0), Papss2 (3.8), Agpat9 (3.1), Ccdc109b (2.8), Phlda2 (2.6), Egln3 (2.5), Gna14 (2.5), Pcsk5 (2.4), Atp1a2 (2.4), Dock10 (2.3), Hs3st3b1 (2.3), Morc4 (2.3), Chst2 (2.3), Pmp22 (2.3), Adamts20 (2.2), St6galnac4 (2.2), Exoc3l (2.2), Fam123c (2.1), Myl7 (2.1), Prdm6 (2.1), Susd5 (2.1), Rbm24 (2.1), Siah2 (2.1), Mex3b (2.1), Chst7 (2.0), Nin (2.0), Actc1 (2.0), Kif26b (2.0), Ccnd2 (2.0), Itih5 (1.9), Man1c1 (1.9), Cbln1 (1.9), Mn1 (1.9), Sh3bp1 (1.9), Fam82a1 (1.8), Olfm1 (1.8), Serpinb9 (1.8), Cdkn1c (1.8), Phldb2 (1.8), Pmaip1 (1.8), Gas1 (1.8), Abtb2 (1.8), Adamts3 (1.7), Sgcb (1.7), Sbsn (1.7), Cyp2s1 (1.7), Adam19 (1.7), Brp44 (1.7), Cyp4f15 (1.7), Dclk1 (1.7), Slco3a1 (1.7), Bace2 (1.7), Car3 (1.7), Aard (1.6), Oaf (1.6), Zadh2 (1.6), As3mt (1.6), Grrp1 (1.6), Ablim1 (1.6), Fam122b (1.6), Gne (1.6), Ptprm (1.6), Rps6ka6 (1.6), Lmna (1.5), Man1a (1.5), Pwwp2b (1.5)

Fold changes are indicated in parentheses. Asterisks indicate genes found only in one of the two array replicates and confirmed by RT-PCR on different biological samples. Bold indicates genes found to be also up-regulated after Mesp1 overexpression.

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