Table I. Genes identified in the S2 cell... | Rockefeller University Press

Table I.

Genes identified in the S2 cell screen and confirmed with nonoverlapping dsRNA

Cg	Gene symbol	Homologue/domain	Z score	Class
8416	Rho1	RhoC	5.8	I
2023	Cg2023	Sec20	3.6	I
7057	AP-50	AP-2µ1	3.2	I
7262	Cg7262	Nucleoporin 93	3.0	I
9156	PP1-13C	PP1cc	3.0	I
3320	Rab1	Rab1A	3.8	II
8385	Arf79F	Arf1	3.3	II
32687	Cg32687	Leucine-rich repeat 58	3.0	II
11427	Ruby	AP-3β2	3.8	III
11197	Garnet	AP-3∂1	3.7	III
8945	Cg8945	Carboxypeptidase	3.4	III
14899	Cg14899	Derlin-2	3.3	III
3201	Mlc-c	Myosin light chain	3.3	III
4707	Cg4707	Zinc finger	3.1	III
1973	Yata	Scy1-like kinase	3.0	III
8027	Cg8027	GlcNAc-1-phosphotransferase (α⁻/β⁻)	3.0	III

Cg	Gene symbol	Homologue/domain	Z score	Class
8416	Rho1	RhoC	5.8	I
2023	Cg2023	Sec20	3.6	I
7057	AP-50	AP-2µ1	3.2	I
7262	Cg7262	Nucleoporin 93	3.0	I
9156	PP1-13C	PP1cc	3.0	I
3320	Rab1	Rab1A	3.8	II
8385	Arf79F	Arf1	3.3	II
32687	Cg32687	Leucine-rich repeat 58	3.0	II
11427	Ruby	AP-3β2	3.8	III
11197	Garnet	AP-3∂1	3.7	III
8945	Cg8945	Carboxypeptidase	3.4	III
14899	Cg14899	Derlin-2	3.3	III
3201	Mlc-c	Myosin light chain	3.3	III
4707	Cg4707	Zinc finger	3.1	III
1973	Yata	Scy1-like kinase	3.0	III
8027	Cg8027	GlcNAc-1-phosphotransferase (α⁻/β⁻)	3.0	III

List of genes identified as positive in the S2 cell screen using GFP-/HA-tagged dVMAT as reporter. The z score indicates significance assessed using a within-plate comparison. Class I dsRNAs increase cell surface expression of DE/AA dVMAT, class II reduce surface expression of the mutant, and class III have no effect.

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