Model variables and parameters
| Symbol | Meaning | Parameter values used | References |
| Stall force of the motor | 1–10 pN | Schnitzer et al., 2000; Valentine et al., 2006 | |
| Detachment force of the motor | 1–10 pN | Valentine et al., 2006 | |
| Maximal velocity of the motor | 0.01–0.5 μm/s | Tao et al., 2006 | |
| Backward velocity of the motor | 0.001–5 μm/s | Carter and Cross, 2005 | |
| Binding rate of motors | 0.01–10 s−1 | Krzysiak et al., 2008 | |
| Load-free detachment rate of motors | 0.01–10 s−1 | Krzysiak et al., 2008 | |
| k, n | Number of bound motors per unit length AP MT | up to 800 μm−1 | Sharp et al., 1999a |
| κ | Spring constant of HL-KLP61F | 10–200 pNs/μm | Tawada and Sekimoto, 1991 |
| ζ(t) | Spring constant of nuclear lamin-B envelope | 100–200 pNs/μm | Dahl et al., 2004; Cytrynbaum et al., 2005 |
| μ | Effective spindle pole viscous drag coefficient | 200 pNs/μm | Marshall et al., 2001 |
| vMT | Instantaneous velocity of MT | variable | This study |
| vpole | Instantaneous velocity of spindle poles | variable | This study |
| νg | MT plus end growth rate | 0.1–0.4 μm/s | Cheerambathur et al., 2007 |
| νs | MT plus end shrinkage rate | 0.1–0.4 μm/s | Cheerambathur et al., 2007 |
| fres | MT plus end rescue frequency | 0.01–0.5 s−1 | Cheerambathur et al., 2007 |
| fcat | MT plus end catastrophe frequency | 0.01–0.5 s−1 | Cheerambathur et al., 2007 |
| Symbol | Meaning | Parameter values used | References |
| Stall force of the motor | 1–10 pN | ||
| Detachment force of the motor | 1–10 pN | ||
| Maximal velocity of the motor | 0.01–0.5 μm/s | ||
| Backward velocity of the motor | 0.001–5 μm/s | ||
| Binding rate of motors | 0.01–10 s−1 | ||
| Load-free detachment rate of motors | 0.01–10 s−1 | ||
| Number of bound motors per unit length AP MT | up to 800 μm−1 | ||
| κ | Spring constant of HL-KLP61F | 10–200 pNs/μm | |
| ζ( | Spring constant of nuclear lamin-B envelope | 100–200 pNs/μm | |
| Effective spindle pole viscous drag coefficient | 200 pNs/μm | ||
| Instantaneous velocity of MT | variable | This study | |
| Instantaneous velocity of spindle poles | variable | This study | |
| νg | MT plus end growth rate | 0.1–0.4 μm/s | |
| νs | MT plus end shrinkage rate | 0.1–0.4 μm/s | |
| MT plus end rescue frequency | 0.01–0.5 s−1 | ||
| MT plus end catastrophe frequency | 0.01–0.5 s−1 |
Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.