Summary of structural components present or absent in WT and drc mutants
| Structural component | Strain | ||||
| WT/pWT | sup-pf-4 | sup-pf-3 | pf2 | pf3 | |
| DRC linker (1,000–1,200) | |||||
| Nexin link connection to neighboring B-tubule | |||||
| Proximal lobe (∼350) | + | + | − | − | − |
| Distal lobe (∼120) | + | +/− | − | − | − |
| Linker projections | |||||
| L1 (50–80) | + | + | +/− | − | +/− |
| L2 | + | − | − | − | − |
| OID linker | + | + | +/− | − | +/− |
| Central linker region | |||||
| Central linker | + | + | +/− | − | +/− |
| Docking subunit (∼60) | + | + | + | + | + |
| DRC base plate (300–350) | |||||
| Base plate protrusion (∼80) | + | + | + | − | − |
| B11-A3 section | + | + | + | + | − |
| Connection to B11 | + | + | + | + | − |
| B-tubule hole | + | + | + | + | − |
| IDAs | |||||
| IA4 | + | + | +/− | +/− | − |
| IA5 | + | + | + | +/− | (−) |
| Structural component | Strain | ||||
| WT/pWT | |||||
| Proximal lobe (∼350) | + | + | − | − | − |
| Distal lobe (∼120) | + | +/− | − | − | − |
| L1 (50–80) | + | + | +/− | − | +/− |
| L2 | + | − | − | − | − |
| OID linker | + | + | +/− | − | +/− |
| Central linker | + | + | +/− | − | +/− |
| Docking subunit (∼60) | + | + | + | + | + |
| Base plate protrusion (∼80) | + | + | + | − | − |
| B11-A3 section | + | + | + | + | − |
| Connection to B11 | + | + | + | + | − |
| B-tubule hole | + | + | + | + | − |
| IA4 | + | + | +/− | +/− | − |
| IA5 | + | + | + | +/− | (−) |
+ indicates that the component is present; +/− indicates that the component reduced; (−) indicates that the component is almost completely reduced; − indicates that the component is lacking. Molecular mass is indicated in parentheses (in kilodaltons).
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