Table I.

Genotype incidence and frequencies of pups and embryos from NuMANeo/+, NuMAflox/+, and NuMAΔ22/+ heterozygous crosses

Parental genotypes Progeny Progeny genotypes 
  + Neo Neo flox flox Δ22 Δ22 
  + + Neo + flox + Δ22 
Neo/+ × Neo/+ Pupsa 23 (26%) 65 (74%) 0 NA NA NA NA 
 Embryosb 21 (42%) 29 (58%) 0 NA NA NA NA 
flox/+ × flox/+ Pups 34 (31%) NA NA 53 (47%) 25 (22%) NA NA 
Δ22/+ × Δ22/+ Pups 14 (33%) NA NA NA NA 28 (67%) 0 
 Embryos 7 (32%) NA NA NA NA 15 (68%) 0 

Neo, NuMANeo; flox, NuMAflox; Δ22, NuMAΔ22; +, wild-type NuMA allele; NA, not applicable.

a

Mouse pups were genotyped at postnatal day 21.

b

Embryos were collected between embryonic days 9.5 and 14.5.

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