Table I.

Members of MCC and associated cytosolic proteins

Name
ORF
Molecular function
Biological process
TMDs
Localization references
Integral MCC     components      
Can1 YEL063C H+-driven arginine permease Basic amino acid transport 12 Malínská et al., 2003  
Fur4 YBR021W H+-driven uracil permease Uracil transport 12 Malínská et al., 2004  
Tat2 YOL020W H+-driven tryptophan and tyrosine permease Aromatic amino acid transport 12 Grossmann et al., 2007  
Nce102 YPR149W Unknown Nonclassical protein secretion 4 This study 
Fmp45 YDL222C Unknown Ascospore formation 4 Young et al., 2002  
Sur7 YML052W Unknown Ascospore formation 4 Malínská et al., 2003; Young et al., 2002  
Ygr131w YGR131W Unknown Unknown 4 This study 
Ylr414c YLR414C Unknown Unknown 4 This study 
Ynl194c YNL194C Unknown Ascospore formation 4 Young et al., 2002  
MCC-associated     cytosolic proteins      
Lsp1 YPL004C Protein kinase inhibitor activity Endocytosis (eisosome) 0 Walther et al., 2006  
Mdg1 YNL173C Unknown Pheromone signaling 0 This study 
Pil1 YGR086C Protein kinase inhibitor activity Endocytosis (eisosome) 0 Walther et al., 2006  
Pkh1 YDR490C Ser/Thr protein kinase Endocytosis 0 Roelants et al., 2002; Walther et al., 2007; Luo et al., 2008  
Pkh2 YOL100W Ser/Thr protein kinase Endocytosis 0 Roelants et al., 2002; Walther et al., 2007; Luo et al., 2008  
Pst2 YDR032C Unknown Unknown 0 This study 
Rfs1 YBR052C Unknown Unknown 0 This study 
Slm1 YIL105C Phosphoinositide binding Actin cytoskeleton organization 0 This study; Fadri et al., 2005  
Slm2 YNL047C Phosphoinositide binding Actin cytoskeleton organization 0 Fadri et al., 2005  
Ycp4 YCR004C Unknown Unknown 0 This study 
Ygr130c YGR130C Unknown Unknown 0 This study 
Ymr031c YMR031C Unknown Unknown 0 This study 

TMD, transmembrane domain. Putative transmembrane domains are given as predicted by TmPred and transmembrane hidden Markov model (TMHMM).

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