Table I.

KLP61F turnover during metaphase and anaphase B in spindles of D. melanogaster embryos

Near pole
Equator

t1/2 in s
% recovery
t1/2 in s
% recovery
Preanaphase B 8.8 ± 0.6 (n = 4) 87 ± 4 (n = 4) 5.9 ± 0.3 (n = 5) 108 ± 7 (n = 5) 
Anaphase B 3.0 ± 0.6 (n = 5) 51 ± 16a (n = 5) 5.4 ± 0.2 (n = 4) 79 ± 10 (n = 4) 
Near pole
Equator

t1/2 in s
% recovery
t1/2 in s
% recovery
Preanaphase B 8.8 ± 0.6 (n = 4) 87 ± 4 (n = 4) 5.9 ± 0.3 (n = 5) 108 ± 7 (n = 5) 
Anaphase B 3.0 ± 0.6 (n = 5) 51 ± 16a (n = 5) 5.4 ± 0.2 (n = 4) 79 ± 10 (n = 4) 
a

Note that this apparent decrease in recovery around the poles is due to the net loss of both tubulin and KLP61F in this region rather than being due to a stable population of KLP61F that turns over slowly (see text).

or Create an Account

Close Modal
Close Modal