| Category . | Ploidy . | CNAs (%) . | |||
|---|---|---|---|---|---|
| Cells derived from xenograft tumor tissues | MDX#10 (CON; n = 351) | MDX#7 (DOX; n = 301) | P value | ||
| Diploid | 10 | 30.6 | <0.00001 | ||
| Tetraploid | 2 | 8 | 0.0003 | ||
| Cultured DLD1CENP-A cells | No DOX (n = 301) | DOX (n = 300) | P value | ||
| Diploid | 10.6 | 31 | <0.00001 | ||
| Tetraploid | 2.3 | 15.3 | 0.0026 | ||
| Category . | Ploidy . | CNAs (%) . | |||
|---|---|---|---|---|---|
| Cells derived from xenograft tumor tissues | MDX#10 (CON; n = 351) | MDX#7 (DOX; n = 301) | P value | ||
| Diploid | 10 | 30.6 | <0.00001 | ||
| Tetraploid | 2 | 8 | 0.0003 | ||
| Cultured DLD1CENP-A cells | No DOX (n = 301) | DOX (n = 300) | P value | ||
| Diploid | 10.6 | 31 | <0.00001 | ||
| Tetraploid | 2.3 | 15.3 | 0.0026 | ||
Quantification of CNAs based on miFISH experiments from Fig. 8 (B and C) showing the proportion of diploid and tetraploid cells with CNA in cells derived from xenograft tumor from mice fed with DOX (MDX#7) or CON diet (MDX#10) or from cultured DLD1CENP-A cells with or without DOX treatment for 4 d. P values were calculated by using Fisher’s exact test in R laboratory.