Table 1.
Nuclear migration kinetics and shape change parameters that differ between hindbrain and retina
ParameterHindbrainRetinaP values
Starting positions (distance to the apical side, μm) 8.4 ± 3.9 6.7 ± 2.04 0.1266 
Variance of starting positions (μm2) 15.01 4.16 0.0485 
Duration of apical migration (min) 13.3 ± 4.5 21.9 ± 7.9 0.0052 
Mean instantaneous velocity (μm/min) 0.63 ± 0.74 0.32 ± 0.77 <0.0001 
Directionality ratio 0.63 ± 0.06 0.36 ± 0.07 – 
Kurtosis of instantaneous velocity distribution 0.32 5.44 – 
Normalized nuclear aspect ratio (S) 0.00 ± 0.09 0.00 ± 0.10 0.7892 
Normalized nuclear aspect ratio (G2) 0.01 ± 0.16 0.17 ± 0.25 <0.0001 
Variance of the normalized nuclear aspect ratio (S) 0.008 0.001 0.02199 
Variance of the normalized nuclear aspect ratio (G2) 0.026 0.063 0.0001 

Values shown represent mean ± SD. P values were calculated using Levene’s test for the variance of starting positions of migration and variances of the normalized nuclear aspect ratio and Mann-Whitney test for starting positions of migration, duration of apical migration, instantaneous velocity, and normalized nuclear aspect ratios. –, not applicable.

[ViewLarge]
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal