Table 1. Differential effect of drugs on... | Rockefeller University Press

Table 1.

Differential effect of drugs on the three cell types

	Jasplakinolide			LatA			LY
	Lifetime	CME productivity	CCS stabilized	Lifetime	CME productivity	CCS stabilized	Lifetime	CME productivity	CCS stabilized
hESCs	+	+	No effect	−	−	+	−	No effect	+
NPCs	No effect	−	+++	−	−	+	−	−	+
Fibroblasts	No effect	No effect	+++	−	+	+	−	+	No effect

	Jasplakinolide			LatA			LY
	Lifetime	CME productivity	CCS stabilized	Lifetime	CME productivity	CCS stabilized	Lifetime	CME productivity	CCS stabilized
hESCs	+	+	No effect	−	−	+	−	No effect	+
NPCs	No effect	−	+++	−	−	+	−	−	+
Fibroblasts	No effect	No effect	+++	−	+	+	−	+	No effect

Table summarizes the different effect of actin and PI-3 kinase drugs on CME of the three cell types. + and – indicate, respectively, an increase or a decrease of the corresponding parameters compared to control condition.

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