Table 1.

IFNAR1/IFNAR2 heterodimer fraction α observed for IFNα2-wt and KDT obtained from the law of mass action

Experimental conditions α KDT a 
  µm−2 
IFNAR2-fl 0.89 0.29 
IFNAR2-fl (primed) 0.41 4.3 
IFNAR2 (−Δ346) 0.84 0.46 
IFNAR2 (−Δ265) 0.36 5.4 
Experimental conditions α KDT a 
  µm−2 
IFNAR2-fl 0.89 0.29 
IFNAR2-fl (primed) 0.41 4.3 
IFNAR2 (−Δ346) 0.84 0.46 
IFNAR2 (−Δ265) 0.36 5.4 
a

Calculated from mean experimental receptor concentrations corrected for the degree of labeling (IFNAR1, 3.5 µm

−; IFNAR2, 1.3 µm−2). Experimental error: ±50%.

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