Genes tested for genetic interaction with Cdc42
| Cdc423/FM7 x | n | Wild type | DC failure/MC failure | Heart defects | P-valuea |
| % | % | % | |||
| w1118 | 662 | 60.7 | 8.5 | 30.8 | |
| ena23 | 27 | 66.7 | 7.4 | 25.9 | 0.68 |
| zfh175.34 | 42 | 64.3 | 0.0 | 35.7 | 0.74 |
| tupisl-1 | 23 | 47.8 | 0.0 | 52.2 | 0.27 |
| zip1 | 30 | 30.0 | 33.3 | 36.7 | 0.001 |
| tinEC40 | 11 | 18.2 | 0.0 | 81.8 | 0.009 |
| tin346 | 29 | 6.9 | 6.9 | 86.2 | <10−8 |
| Abl2 | 28 | 19.9 | 25 | 57.1 | <10−4 |
| tinCΔ4>diaCA | 19 | 0 | 5 | 14 | <10−7 |
| Cdc423,dDAAMex68 | 22 | 18.2 | 81.8 | <10−4 |
| Cdc423/FM7 x | n | Wild type | DC failure/MC failure | Heart defects | P-valuea |
| % | % | % | |||
| w1118 | 662 | 60.7 | 8.5 | 30.8 | |
| ena23 | 27 | 66.7 | 7.4 | 25.9 | 0.68 |
| zfh175.34 | 42 | 64.3 | 0.0 | 35.7 | 0.74 |
| tupisl-1 | 23 | 47.8 | 0.0 | 52.2 | 0.27 |
| zip1 | 30 | 30.0 | 33.3 | 36.7 | 0.001 |
| tinEC40 | 11 | 18.2 | 0.0 | 81.8 | 0.009 |
| tin346 | 29 | 6.9 | 6.9 | 86.2 | <10−8 |
| Abl2 | 28 | 19.9 | 25 | 57.1 | <10−4 |
| tinCΔ4>diaCA | 19 | 0 | 5 | 14 | <10−7 |
| Cdc423,dDAAMex68 | 22 | 18.2 | 81.8 | <10−4 |
Embryos hemizygous for Cdc423 and heterozygous for the indicated alleles were phenotypically analyzed.
Fisher’s exact test was applied to test for significant differences in the expected number of wild-type hearts vs. mutant hearts.