Table 1. Time taken from nocodazole... | Rockefeller University Press

Table 1.

Time taken from nocodazole release for substrate levels to reach 20% of the starting level in control cells

Substrate	Control siRNA	siMAD2L2	siMAD2L2:hMAD2L2-myc
Cyclin B1	73.6 ± 2	32.1 ± 10.2	95.7 ± 20
Securin	69.7 ± 2.2	48.5 ± 12.6	57.9 ± 12
Cdc20	118 ± 1.5	67.9 ± 12.2	122 ± 44.3
AURKA	179 ± 14.8	61.3 ± 15.3	180 ± 60.3
UBCH10	248 ± 4.2	214 ± 55.8	234 ± 102
MAD2L2	119 ± 1	–	251 ± 75

Substrate	Control siRNA	siMAD2L2	siMAD2L2:hMAD2L2-myc
Cyclin B1	73.6 ± 2	32.1 ± 10.2	95.7 ± 20
Securin	69.7 ± 2.2	48.5 ± 12.6	57.9 ± 12
Cdc20	118 ± 1.5	67.9 ± 12.2	122 ± 44.3
AURKA	179 ± 14.8	61.3 ± 15.3	180 ± 60.3
UBCH10	248 ± 4.2	214 ± 55.8	234 ± 102
MAD2L2	119 ± 1	–	251 ± 75

Calculated from fitted exponential decay curves (Fig. 2 E).