Hemodynamic parameters of vessels observed by intravital microscopy
| Genotype . | Diameter (μm) . | Newtonian wall shear rate γw (s−1) . | Interfacial shear rate γi (1000 s−1) . |
|---|---|---|---|
| Adamts13+/+/Vwf+/+ (n = 10) | 31.4 ± 4.5 | 276.1 ± 43.6 | 1.35 ± 0.45 |
| Adamts13−/−/Vwf+/+ (n = 12) | 30.1 ± 4.3 | 282.6 ± 83.1 | 1.38 ± 0.57 |
| Adamts13−/−/Vwf−/− (n = 10) | 34.7 ± 6 | 257.9 ± 53 | 1.26 ± 0.26 |
| Adamts13+/+/Vwf−/− (n = 9) | 31.3 ± 5 | 265.1 ± 72.3 | 1.3 ± 0.56 |
| Genotype . | Diameter (μm) . | Newtonian wall shear rate γw (s−1) . | Interfacial shear rate γi (1000 s−1) . |
|---|---|---|---|
| Adamts13+/+/Vwf+/+ (n = 10) | 31.4 ± 4.5 | 276.1 ± 43.6 | 1.35 ± 0.45 |
| Adamts13−/−/Vwf+/+ (n = 12) | 30.1 ± 4.3 | 282.6 ± 83.1 | 1.38 ± 0.57 |
| Adamts13−/−/Vwf−/− (n = 10) | 34.7 ± 6 | 257.9 ± 53 | 1.26 ± 0.26 |
| Adamts13+/+/Vwf−/− (n = 9) | 31.3 ± 5 | 265.1 ± 72.3 | 1.3 ± 0.56 |
Hemodynamic parameters were established before recording leukocyte adhesion for Fig. 4. Values are represented as mean ± SD. P = NS.