Table 1.
Summary showing CI, LVP, and HR under various contractile conditions
MyofibrilFrequencyTotal number of sarcomeresCIAvg. CIDiastolic LVP (mm Hg)Systolic LVP (mm Hg)ΔLVP (mm Hg)HR (bpm)
 CI > 0.2 0.2 > CI > 0 CI < 0        
M1 5 0 0 5 0.51 ± 0.06 0.48 ± 0.24 −3.8 ± 0.1 131.9 ± 1.4 135.7 ± 1.5 496 ± 0.4 
M2 5 1 0 6 0.42 ± 0.12 
M3 4 0 1 5 0.54 ± 0.43 
M1 20 7 3 30 0.30 ± 0.22 0.29 ± 0.20 −4.5 ± 1.2 88.6 ± 3.1 96.4 ± 4.7 469 ± 2.9 
M2 23 5 2 30 0.29 ± 0.19 
M1 8 4 4 16 0.20 ± 0.24 0.26 ± 0.25 −0.5 ± 0.1 61.2 ± 1.1 60.5 ± 4.2 581 ± 6.6 
M2 9 4 1 14 0.33 ± 0.25 
M1 21 5 6 32 0.32 ± 0.36 0.27 ± 0.33 0.5 ± 0.1 42.1 ± 0.4 40.6 ± 2.5 347 ± 7.9 
M2 22 5 8 35 0.22 ± 0.31 
M1 5 4 0 9 0.25 ± 0.16 0.23 ± 0.16 13.3 ± 0.1 20.2 ± 0.1 7.2 ± 0.1 159 ± 45.4 
M2 4 4 1 9 0.21 ± 0.17 
M1 2 4 1 7 0.17 ± 0.27 0.17 ± 0.24 9.9± 0.1 14.6 ± 0.2 4.7 ± 0.2 80 ± 14.2 
M2 3 2 2 7 0.17 ± 0.24 
M3 3 3 1 7 0.20 ± 0.23 

Data were taken from Fig. S15 (135.7 mm Hg), Fig. 3 (96.4 mm Hg), Fig. S6 (60.5 and 40.6 mm Hg), and Fig. S18 (7.2 and 4.7 mm Hg). Two or three myofibrils were analyzed in one mouse, each of which provided the fraction of CI (two myofibrils, 96.4, 60.5, 40.6, and 7.2 mm Hg; three myofibrils, 135.7 and 4.7 mm Hg). Avg. CI indicates the average value of CI of individual sarcomeres in analyzed myofibrils (see Fig. 4 D).

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