Table 1.
Quantifying the effect of lowering [Ca2+]o on CTCs in ICC-MY
CTC parameters2.5 mM [Ca2+]o1 mM [Ca2+]o0.5 mM [Ca2+]o0 mM [Ca2+]o
Probability (%) of Ca2+ site firing/CTC cycle (somata) 64.7 ± 2.3 19.8 ± 1.9 1.4 ± 0.5 0 
Probability (%) of Ca2+ site firing/CTC cycle (processes) 65.7 ± 1.6 18.2 ± 1.3 5.8 ± 0.9 0 
No. of Ca2+ sites/soma 4.8 ± 1 2.09 ± 0.27 0.29 ± 0.07 0 
No. of Ca2+ sites/process FOV 55.67 ± 13 27.67 ± 3.96 9.33 ± 4.04 0 
PTCL area/frame (µm2) somata 30.77 ± 10.23 6.73 ± 1.76 0.28 ± 0.18 0 
PTCL area/frame (µm2) processes 80.71 ± 29 13.17 ± 2.88 15.67 ± 13.23 0 
PTCL count/frame somata 0.84 ± 0.2 0.28 ± 0.06 0.02 ± 0.01 0 
PTCL count/frame processes 2.28 ± 0.56 0.71 ± 0.14 0.13 ± 0.08 0 
CTC parameters2.5 mM [Ca2+]o1 mM [Ca2+]o0.5 mM [Ca2+]o0 mM [Ca2+]o
Probability (%) of Ca2+ site firing/CTC cycle (somata) 64.7 ± 2.3 19.8 ± 1.9 1.4 ± 0.5 0 
Probability (%) of Ca2+ site firing/CTC cycle (processes) 65.7 ± 1.6 18.2 ± 1.3 5.8 ± 0.9 0 
No. of Ca2+ sites/soma 4.8 ± 1 2.09 ± 0.27 0.29 ± 0.07 0 
No. of Ca2+ sites/process FOV 55.67 ± 13 27.67 ± 3.96 9.33 ± 4.04 0 
PTCL area/frame (µm2) somata 30.77 ± 10.23 6.73 ± 1.76 0.28 ± 0.18 0 
PTCL area/frame (µm2) processes 80.71 ± 29 13.17 ± 2.88 15.67 ± 13.23 0 
PTCL count/frame somata 0.84 ± 0.2 0.28 ± 0.06 0.02 ± 0.01 0 
PTCL count/frame processes 2.28 ± 0.56 0.71 ± 0.14 0.13 ± 0.08 0 
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