Table 1.

Demographic characteristics of Latin American patients with CGD (n = 238)

TotalXL-CGDAR-CGDAR-CGD + UGfemUG-CGD
No. of patients, n (%) 238 (100) 109 (46) 32 (13) 52 (29) 97 (41) 
Family, n 210 94 28 47 88 
Consanguinity, n (%) 22 (10) 3 (3) 13 (46) 14 (30) 6 (6.2) 
Family history of CGD, n (%) 41 (19) 22 (23) 5 (18) 8 (17) 14 (14.4) 
Outcome 
Undergoing HSTC, n (%) 53 (22) 22 (20) 5 (16) 8 (15) 26 (26.8) 
HSCT deceased, n (%) 16 (30) 7 (31) 2 (40) 2 (25) 7 (27) 
Deceased, n (%) 80 (34) 43 (54)* 4 (5) 12 (15)* 33 (34) 
Age of death 66m (1m–31y2m) 60.5m (5m–31y2m) 133.5m (2 years–19y6m) 88m (1y5m–23y) 75m (1m–25y) 
TotalXL-CGDAR-CGDAR-CGD + UGfemUG-CGD
No. of patients, n (%) 238 (100) 109 (46) 32 (13) 52 (29) 97 (41) 
Family, n 210 94 28 47 88 
Consanguinity, n (%) 22 (10) 3 (3) 13 (46) 14 (30) 6 (6.2) 
Family history of CGD, n (%) 41 (19) 22 (23) 5 (18) 8 (17) 14 (14.4) 
Outcome 
Undergoing HSTC, n (%) 53 (22) 22 (20) 5 (16) 8 (15) 26 (26.8) 
HSCT deceased, n (%) 16 (30) 7 (31) 2 (40) 2 (25) 7 (27) 
Deceased, n (%) 80 (34) 43 (54)* 4 (5) 12 (15)* 33 (34) 
Age of death 66m (1m–31y2m) 60.5m (5m–31y2m) 133.5m (2 years–19y6m) 88m (1y5m–23y) 75m (1m–25y) 

General demographic characteristics of Latin American CGD patients by genotype/phenotype (XL-CGD, AR-CGD, AR-CGD + UGfem, and UG-CGD) and total. For statistical purposes, UGfem were included in the AR-CGD group, forming the group AR-CGD + UGfem. y, year; m, month. *χ2 test (P = 0.041).

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