Comparison of HLA class I markers between 161 TACI patients and 1,241 unsolved PAD patients
| HLA . | % in TACI patients . | % in Other PADs . | P value . | FDR-adjusted P value . | HLA . | % in TACI patients . | % in Other PADs . | P value . | FDR-adjusted P value . |
|---|---|---|---|---|---|---|---|---|---|
| A*01 | 8.1 | 18.0 | 0.058447 | 0.409132 | B*42 | 0.0 | 1.0 | 1 | 1.615385 |
| A*02 | 18.0 | 18.0 | 0.87997 | 1.637412 | B*44 | 1.9 | 14.0 | 0.004143 | 0.055364 |
| A*03 | 11.8 | 12.0 | 1 | 1.814815 | B*45 | 1.2 | 0.0 | 1 | 1.597826 |
| A*11 | 8.1 | 16.0 | 0.127714 | 0.647377 | B*46 | 0.0 | 1.0 | 1 | 1.580645 |
| A*23 | 3.1 | 1.0 | 0.613505 | 1.346049 | B*47 | 0.0 | 1.0 | 1 | 1.56383 |
| A*24 | 16.8 | 7.0 | 0.050186 | 0.388283 | B*49 | 3.7 | 1.0 | 0.36503 | 1.16651 |
| A*25 | 1.2 | 2.0 | 1 | 1.792683 | B*50 | 5.0 | 1.0 | 0.213669 | 0.848901 |
| A*26 | 6.8 | 2.0 | 0.172446 | 0.745577 | B*51 | 13.0 | 9.0 | 0.497786 | 1.143353 |
| A*29 | 1.9 | 4.0 | 0.678498 | 1.366291 | B*52 | 6.8 | 1.0 | 0.071197 | 0.418638 |
| A*30 | 3.7 | 8.0 | 0.37173 | 1.092887 | B*53 | 1.2 | 2.0 | 1 | 1.547368 |
| A*31 | 1.9 | 2.0 | 1 | 1.771084 | B*54 | 0.0 | 1.0 | 1 | 1.53125 |
| A*32 | 8.1 | 5.0 | 0.5662 | 1.280482 | B*55 | 3.7 | 4.0 | 1 | 1.515464 |
| A*33 | 3.7 | 1.0 | 0.36503 | 1.219533 | B*56 | 1.2 | 1.0 | 1 | 1.5 |
| A*34 | 0.0 | 1.0 | 1 | 1.75 | B*57 | 1.9 | 3.0 | 1 | 1.484848 |
| A*66 | 1.2 | 1.0 | 1 | 1.729412 | B*58 | 1.9 | 6.0 | 0.279016 | 0.976557 |
| A*68 | 3.7 | 0.0 | 0.129714 | 0.635601 | B*78 | 1.2 | 1.0 | 1 | 1.47 |
| A*69 | 1.2 | 0.0 | 1 | 1.709302 | C*01 | 3.7 | 4.0 | 1 | 1.455446 |
| A*74 | 0.0 | 4.0 | 0.129714 | 0.615098 | C*02 | 1.2 | 4.0 | 0.36503 | 1.14169 |
| B*07 | 3.1 | 4.0 | 1 | 1.689655 | C*03 | 1.9 | 8.0 | 0.104757 | 0.592283 |
| B*08 | 3.7 | 14.0 | 0.026165 | 0.256421 | C*04 | 24.2 | 12.0 | 0.042911 | 0.350438 |
| B*13 | 5.0 | 2.0 | 0.441587 | 1.22478 | C*05 | 1.2 | 6.0 | 0.123797 | 0.674005 |
| B*14 | 3.7 | 1.0 | 0.36503 | 1.192432 | C*06 | 9.9 | 9.0 | 1 | 1.441176 |
| B*15 | 1.9 | 3.0 | 1 | 1.670455 | C*07 | 19.9 | 20.0 | 1 | 1.427184 |
| B*18 | 3.7 | 5.0 | 1 | 1.651685 | C*08 | 3.1 | 2.0 | 1 | 1.413462 |
| B*27 | 1.2 | 3.0 | 0.620596 | 1.303251 | C*12 | 16.1 | 9.0 | 0.199543 | 0.838082 |
| B*35 | 19.3 | 9.0 | 0.066645 | 0.408198 | C*14 | 3.7 | 8.0 | 0.37173 | 1.071458 |
| B*37 | 0.0 | 2.0 | 0.477289 | 1.252885 | C*15 | 8.1 | 8.0 | 1 | 1.4 |
| B*38 | 5.0 | 1.0 | 0.213669 | 0.872481 | C*16 | 1.9 | 4.0 | 0.678498 | 1.347828 |
| B*39 | 1.9 | 3.0 | 0.991011 | 1.820983 | C*17 | 3.7 | 3.0 | 1 | 1.386792 |
| B*40 | 3.1 | 6.0 | 0.495117 | 1.155273 | C*18 | 0.0 | 1.0 | 1 | 1.373832 |
| B*41 | 4.0 | 3.0 | 1 | 1.633333 | | | | | |
| HLA . | % in TACI patients . | % in Other PADs . | P value . | FDR-adjusted P value . | HLA . | % in TACI patients . | % in Other PADs . | P value . | FDR-adjusted P value . |
|---|---|---|---|---|---|---|---|---|---|
| A*01 | 8.1 | 18.0 | 0.058447 | 0.409132 | B*42 | 0.0 | 1.0 | 1 | 1.615385 |
| A*02 | 18.0 | 18.0 | 0.87997 | 1.637412 | B*44 | 1.9 | 14.0 | 0.004143 | 0.055364 |
| A*03 | 11.8 | 12.0 | 1 | 1.814815 | B*45 | 1.2 | 0.0 | 1 | 1.597826 |
| A*11 | 8.1 | 16.0 | 0.127714 | 0.647377 | B*46 | 0.0 | 1.0 | 1 | 1.580645 |
| A*23 | 3.1 | 1.0 | 0.613505 | 1.346049 | B*47 | 0.0 | 1.0 | 1 | 1.56383 |
| A*24 | 16.8 | 7.0 | 0.050186 | 0.388283 | B*49 | 3.7 | 1.0 | 0.36503 | 1.16651 |
| A*25 | 1.2 | 2.0 | 1 | 1.792683 | B*50 | 5.0 | 1.0 | 0.213669 | 0.848901 |
| A*26 | 6.8 | 2.0 | 0.172446 | 0.745577 | B*51 | 13.0 | 9.0 | 0.497786 | 1.143353 |
| A*29 | 1.9 | 4.0 | 0.678498 | 1.366291 | B*52 | 6.8 | 1.0 | 0.071197 | 0.418638 |
| A*30 | 3.7 | 8.0 | 0.37173 | 1.092887 | B*53 | 1.2 | 2.0 | 1 | 1.547368 |
| A*31 | 1.9 | 2.0 | 1 | 1.771084 | B*54 | 0.0 | 1.0 | 1 | 1.53125 |
| A*32 | 8.1 | 5.0 | 0.5662 | 1.280482 | B*55 | 3.7 | 4.0 | 1 | 1.515464 |
| A*33 | 3.7 | 1.0 | 0.36503 | 1.219533 | B*56 | 1.2 | 1.0 | 1 | 1.5 |
| A*34 | 0.0 | 1.0 | 1 | 1.75 | B*57 | 1.9 | 3.0 | 1 | 1.484848 |
| A*66 | 1.2 | 1.0 | 1 | 1.729412 | B*58 | 1.9 | 6.0 | 0.279016 | 0.976557 |
| A*68 | 3.7 | 0.0 | 0.129714 | 0.635601 | B*78 | 1.2 | 1.0 | 1 | 1.47 |
| A*69 | 1.2 | 0.0 | 1 | 1.709302 | C*01 | 3.7 | 4.0 | 1 | 1.455446 |
| A*74 | 0.0 | 4.0 | 0.129714 | 0.615098 | C*02 | 1.2 | 4.0 | 0.36503 | 1.14169 |
| B*07 | 3.1 | 4.0 | 1 | 1.689655 | C*03 | 1.9 | 8.0 | 0.104757 | 0.592283 |
| B*08 | 3.7 | 14.0 | 0.026165 | 0.256421 | C*04 | 24.2 | 12.0 | 0.042911 | 0.350438 |
| B*13 | 5.0 | 2.0 | 0.441587 | 1.22478 | C*05 | 1.2 | 6.0 | 0.123797 | 0.674005 |
| B*14 | 3.7 | 1.0 | 0.36503 | 1.192432 | C*06 | 9.9 | 9.0 | 1 | 1.441176 |
| B*15 | 1.9 | 3.0 | 1 | 1.670455 | C*07 | 19.9 | 20.0 | 1 | 1.427184 |
| B*18 | 3.7 | 5.0 | 1 | 1.651685 | C*08 | 3.1 | 2.0 | 1 | 1.413462 |
| B*27 | 1.2 | 3.0 | 0.620596 | 1.303251 | C*12 | 16.1 | 9.0 | 0.199543 | 0.838082 |
| B*35 | 19.3 | 9.0 | 0.066645 | 0.408198 | C*14 | 3.7 | 8.0 | 0.37173 | 1.071458 |
| B*37 | 0.0 | 2.0 | 0.477289 | 1.252885 | C*15 | 8.1 | 8.0 | 1 | 1.4 |
| B*38 | 5.0 | 1.0 | 0.213669 | 0.872481 | C*16 | 1.9 | 4.0 | 0.678498 | 1.347828 |
| B*39 | 1.9 | 3.0 | 0.991011 | 1.820983 | C*17 | 3.7 | 3.0 | 1 | 1.386792 |
| B*40 | 3.1 | 6.0 | 0.495117 | 1.155273 | C*18 | 0.0 | 1.0 | 1 | 1.373832 |
| B*41 | 4.0 | 3.0 | 1 | 1.633333 | | | | | |